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Antibody Product Overview
| ELK.No | ES18062 |
| Product name | BEX2 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 84707 |
| Human Swiss-Prot | Q9BXY8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | BEX2 |
| Fields | |
| Gene name | BEX2 |
| Protein name | BEX2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 12069 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9WTZ8 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 363498 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q3MKQ1 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human BEX2 AA range: 28-78 |
| Specificity | This antibody detects endogenous levels of BEX2 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 14kD |
| Observed band (KD) | |
| Background | This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009], |
| Function | caution:Was named BEX1 by some authors.,similarity:Belongs to the BEX family.,subunit:Interacts with OMP (By similarity). Interacts with LMO2, possibly leading to regulate the transcriptional activity of a DNA-binding complex containing LMO2.,tissue specificity:Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe., |
| Subcellular location | Cytoplasm . Nucleus . |
| Expression | Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe. Widely expressed in breast cancer cell lines. |
Additional Images
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Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18062-100
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