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Antibody Product Overview
| ELK.No | ES18194 |
| Product name | ATOH1 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | Protein atonal homolog 1 (Class A basic helix-loop-helix protein 14) (bHLHa14) (Helix-loop-helix protein hATH-1) (hATH1) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 474 |
| Human Swiss-Prot | Q92858 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ATOH1 |
| Fields | |
| Gene name | ATOH1 ATH1 BHLHA14 |
| Protein name | ATOH1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 11921 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P48985 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human ATOH1 AA range: 38-88 |
| Specificity | This antibody detects endogenous levels of ATOH1 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.46% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 38kD |
| Background | This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47. [provided by RefSeq, Jul 2008], |
| Function | function:Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. May play a role in the differentiation of subsets of neural cells by activating E box-dependent transcription.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein., |
| Subcellular location | Nucleus . |
| Expression | PCR rescued clones, |
Additional Images
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Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18194-50
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