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Antibody Product Overview
| ELK.No | ES18199 |
| Product name | ATL4 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 54507 |
| Human Swiss-Prot | Q6UY14 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ATL4 |
| Fields | |
| Gene name | ADAMTSL4 TSRC1 PP1396 UNQ2803/PRO34012 |
| Protein name | ATL4 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 229595 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q80T21 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 310670 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q4FZU4 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human ATL4 AA range: 78-128 |
| Specificity | This antibody detects endogenous levels of ATL4 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 118kD |
| Observed band (KD) | |
| Background | This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Sep 2014], |
| Function | caution:Although similar to members of the ADAMTS family, it lacks the metalloprotease and disintegrin-like domains which are typical of that family.,function:Positive regulation of apoptosis.,similarity:Contains 1 PLAC domain.,similarity:Contains 6 TSP type-1 domains.,subunit:Interacts with CTSB., |
| Subcellular location | Secreted, extracellular space, extracellular matrix . Colocalizes with FMN1 microfibrils in the eye ECM. |
| Expression | Expressed in colon, heart, leukocyte, liver, lung, skeletal muscle, spleen, testis and placenta. Weaker expression in bone marrow, brain tissue, kidney and pancreas. Expression studies in fetal tissues reveal strong expression in heart, kidney, liver, lung and skeletal muscle, but weaker expression in fetal brain and skin. |
Additional Images
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Western blot analysis of lysates from PC-12 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18199-100
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