ATAD5 rabbit pAb

ATAD5 rabbit pAb

AO-06-ES18217-100

ATAD5 rabbit pAb 100μL

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€429.00
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Antibody Product Overview

ELK.NoES18217
Product nameATAD5 rabbit pAb
ReactivityHuman; Mouse
ApplicationsWB
Other name
Size100μL
Unit price ($)248
Human gene ID79915
Human Swiss-ProtQ96QE3
SourceRabbit
IsotypeIgG
TargetATAD5
Fields
Gene nameATAD5 C17orf41 FRAG1
Protein nameATAD5
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID237877
Mouse gene linkView Mouse Gene
Mouse Swiss-ProtQ4QY64
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenSynthesized peptide derived from human ATAD5 AA range: 1054-1104
SpecificityThis antibody detects endogenous levels of ATAD5 at Human/Mouse
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)203kD
Observed band (KD)
Background
Functionfunction:Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages-induced apoptosis.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. ATR may stimulate the RAD9A dissociation.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the AAA ATPase family.,subunit:Interacts with RB1 predominantly in G1 phase via its LXCXE motif. Interacts with RAD9A in growing cells. The interaction with RAD9A is reduced after exposure to DNA replication-inhibiting agents.,
Subcellular locationNucleus .
Expression

Additional Images

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Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18217-100
: 10 Items
Hurry! only 10 items left in stock.

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