| ELK.No | ES18364 |
| Product name | AMZ2 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 51321 |
| Human Swiss-Prot | Q86W34 |
| Source | Rabbit |
| Isotype | IgG |
| Target | AMZ2 |
| Fields | |
| Gene name | AMZ2 BM-014 |
| Protein name | AMZ2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 13929 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q400C8 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 360650 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q400C7 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human AMZ2 AA range: 99-149 |
| Specificity | This antibody detects endogenous levels of AMZ2 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 40kD |
| Observed band (KD) | |
| Background | |
| Function | caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,enzyme regulation:Inhibited by the general metalloprotease inhibitors o-phenanthroline and batimastat. Also significantly inhibited by amastatin, which is an inhibitor of aminopeptidases. Not inhibited by 4-(2-aminoethyl)-benzenesulfonyl fluoride, E-64, and TIMPS (tissue inhibitors of metalloproteinases), which are inhibitors of serine, cysteine, and matrix metalloproteases, respectively.,function:Zinc metalloprotease. Exhibits activity against angiotensin-3 in vitro. Does not hydrolyze either neurogranin or angiotensin-2.,sequence caution:Translated as Gly.,similarity:Belongs to the peptidase archaemetzincin family.,tissue specificity:Predominantly expressed in heart and testis. Also expressed at lower levels in kidney, liver, pancreas, lung, brain and pla |
| Subcellular location | |
| Expression | Down-regulated in testis from patients with maturation arrest (MA) or Sertoli cell-only syndrome (SCOS). |

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