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Antibody Product Overview
| ELK.No | ES18410 |
| Product name | AL1L1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 10840 |
| Human Swiss-Prot | O75891 |
| Source | Rabbit |
| Isotype | IgG |
| Target | AL1L1 |
| Fields | >>One carbon pool by folate;>>Metabolic pathways |
| Gene name | ALDH1L1 FTHFD |
| Protein name | AL1L1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 107747 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8R0Y6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 64392 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P28037 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human AL1L1 AA range: 512-562 |
| Specificity | This antibody detects endogenous levels of AL1L1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 99kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012], |
| Function | catalytic activity:10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) + NADPH.,similarity:Belongs to the aldehyde dehydrogenase family.,similarity:Contains 1 acyl carrier domain.,similarity:In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.,similarity:In the N-terminal section; belongs to the GART family., |
| Subcellular location | Cytoplasm, cytosol . |
| Expression | Highly expressed in liver, pancreas and kidney. |
Additional Images
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Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18410-100
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