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Antibody Product Overview
| ELK.No | ES18423 |
| Product name | AKIR2 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 55122 |
| Human Swiss-Prot | Q53H80 |
| Source | Rabbit |
| Isotype | IgG |
| Target | AKIR2 |
| Fields | |
| Gene name | AKIRIN2 C6orf166 |
| Protein name | AKIR2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 433693 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | B1AXD8 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 297968 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q25C79 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human AKIR2 AA range: 14-64 |
| Specificity | This antibody detects endogenous levels of AKIR2 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 22kD |
| Observed band (KD) | |
| Background | |
| Function | function:Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1.,miscellaneous:'Akiraka ni suru' means 'making things clear' in Japanese. The name is given based on the presence of the clear nuclear localization signal.,similarity:Belongs to the akirin family.,subunit:Interacts with YWHAB.,tissue specificity:Widely expressed with the highest expression in peripheral blood leukocytes., |
| Subcellular location | Nucleus . Cytoplasm . Membrane . Present mainly in the nuclear fraction, and at much lower level in the cytoplasmic and membrane fractions. . |
| Expression | Widely expressed with the highest expression in peripheral blood leukocytes. |
Additional Images
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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18423-50
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