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Antibody Product Overview
| ELK.No | ES1893 |
| Product name | CD108 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | SEMA7A; CD108; SEMAL; Semaphorin-7A; CDw108; JMH blood group antigen; John-Milton-Hargen human blood group Ag; Semaphorin-K1; Sema K1; Semaphorin-L; Sema L; CD antigen CD108 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 8482 |
| Human Swiss-Prot | O75326 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CD108 |
| Fields | >>Axon guidance |
| Gene name | SEMA7A |
| Protein name | Semaphorin-7A |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 20361 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9QUR8 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from CD108 . at AA range: 150-230 |
| Specificity | CD108 Polyclonal Antibody detects endogenous levels of CD108 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 75kD |
| Background | This gene encodes a member of the semaphorin family of proteins. The encoded preproprotein is proteolytically processed to generate the mature glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein. The encoded protein is found on activated lymphocytes and erythrocytes and may be involved in immunomodulatory and neuronal processes. The encoded protein carries the John Milton Hagen (JMH) blood group antigens. Mutations in this gene may be associated with reduced bone mineral density (BMD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016], |
| Function | function:May play an imortant role in the nervous system and in modulating immune function.,online information:Blood group antigen gene mutation database,similarity:Belongs to the semaphorin family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 PSI domain.,similarity:Contains 1 Sema domain.,tissue specificity:Expressed in placenta, testis, ovary, spleen, brain, spinal chord, lung, heart, adrenal gland, lymph nodes, thymus, intestine and kidney., |
| Subcellular location | Cell membrane ; Lipid-anchor, GPI-anchor ; Extracellular side . Detected in a punctate pattern on the cell membrane of basal and supra-basal skin keratinocytes. |
| Expression | Detected in skin keratinocytes and on endothelial cells from skin blood vessels (at protein level). Expressed in fibroblasts, keratinocytes, melanocytes, placenta, testis, ovary, spleen, brain, spinal chord, lung, heart, adrenal gland, lymph nodes, thymus, intestine and kidney. |
Additional Images
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Western Blot analysis of various cells using CD108 Polyclonal Antibody
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: AO-06-ES1893-100
: 10 Items
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