CD2BP2 rabbit pAb

CD2BP2 rabbit pAb

AO-06-ES1904-50

CD2BP2 rabbit pAb 50μL

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€299.00
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Antibody Product Overview

ELK.NoES1904
Product nameCD2BP2 rabbit pAb
ReactivityHuman;Monkey
ApplicationsWB;IHC;IF;ELISA
Other nameCD2BP2; KIAA1178; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; CD2 tail-binding protein 2
Size50μL
Unit price ($)148
Human gene ID10421
Human Swiss-ProtO95400
SourceRabbit
IsotypeIgG
TargetCD2BP2
Fields
Gene nameCD2BP2
Protein nameCD2 antigen cytoplasmic tail-binding protein 2
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID
Mouse gene link
Mouse Swiss-ProtQ9CWK3
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenThe antiserum was produced against synthesized peptide derived from human CD2 Tail-binding. AA range:101-150
SpecificityCD2BP2 Polyclonal Antibody detects endogenous levels of CD2BP2 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)50kD
BackgroundThis gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008],
Functionsimilarity:Contains 1 GYF domain.,subunit:Binds the cytoplasmic domain of CD2 through the GYF domain.,
Subcellular locationCytoplasm. Nucleus. Predominantly nuclear.
ExpressionAorta,Brain,Epithelium,Liver,Lung,

Additional Images

Image 1
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Western Blot analysis of various cells using CD2BP2 Polyclonal Antibody diluted at 1:1000
Image 2
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Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
Image 3
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Western blot analysis of lysates from COS7 cells, using CD2 Tail-binding Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from HeLa cells using CD2 Tail-binding antibody.
: AO-06-ES1904-50
: 10 Items
Hurry! only 10 items left in stock.

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