Français
English
Antibody Product Overview
| ELK.No | ES2117 |
| Product name | Cystatin 11 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | CST11; CST8L; Cystatin-11 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 140880 |
| Human Swiss-Prot | Q9H112 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Cystatin 11 |
| Fields | |
| Gene name | CST11 |
| Protein name | Cystatin-11 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q9D269 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CST11. AA range:81-130 |
| Specificity | Cystatin 11 Polyclonal Antibody detects endogenous levels of Cystatin 11 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 17kD |
| Background | The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes an epididymal-specific protein shown to have antimicrobial activity against E. coli. Alternative splicing yields two variants encoding distinct isoforms. [provided by RefSeq, Sep 2014], |
| Function | function:Has antibacterial activity against the Gram-negative bacteria E.coli. May play a role in sperm maturation and fertilization.,similarity:Belongs to the cystatin family.,subcellular location:Nuclear and cytoplasmic in the epididymis. Localized to the postacrosomal and tail regions of sperm. Probably localized to the outer surface of sperm.,tissue specificity:Detected in the epithelium and lumen of the epididymis, and in sperm (at protein level)., |
| Subcellular location | Secreted . Probably secreted into the epididymis lumen, where it localizes to the outer surface of sperm. Specifically localizes to the postacrosomal and tail regions of sperm. . |
| Expression | Detected in the epithelium and lumen of the epididymis, and in sperm (at protein level). |
Additional Images
No image
Western Blot analysis of various cells using Cystatin 11 Polyclonal Antibody
No image
Western blot analysis of the lysates from Jurkat cells using CST11 antibody.
No image
No image
: AO-06-ES2117-50
: 10 Items
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package