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Antibody Product Overview
| ELK.No | ES2149 |
| Product name | DBP rabbit pAb |
| Reactivity | Human;Monkey |
| Applications | WB;ELISA |
| Other name | GC; Vitamin D-binding protein; DBP; VDB; Gc-globulin; Group-specific component |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 2638 |
| Human Swiss-Prot | P02774 |
| Source | Rabbit |
| Isotype | IgG |
| Target | DBP |
| Fields | |
| Gene name | GC |
| Protein name | Vitamin D-binding protein |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P21614 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from DBP . at AA range: 90-170 |
| Specificity | DBP Polyclonal Antibody detects endogenous levels of DBP protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 55kD |
| Background | The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011], |
| Function | function:Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.,polymorphism:Over 80 variants of human DBP have been identified. The three most common alleles are called GC*1F, GC*1S, and GC*2. The sequence shown is that of the GC*2 allele.,similarity:Belongs to the ALB/AFP/VDB family.,similarity:Contains 3 albumin domains., |
| Subcellular location | Secreted . |
| Expression | Expressed in the liver. Found in plasma, ascites, cerebrospinal fluid and urine. |
Additional Images
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Western Blot analysis of various cells using DBP Polyclonal Antibody
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Western Blot analysis of COS7 cells using DBP Polyclonal Antibody
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: AO-06-ES2149-50
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