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Antibody Product Overview
| ELK.No | ES2167 |
| Product name | D-GPCR rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IF;ELISA |
| Other name | OR51E1; GPR164; OR51E1P; OR52A3P; POGR; PSGR2; Olfactory receptor 51E1; D-GPCR; G-protein coupled receptor 164; Olfactory receptor 52A3; Prostate-overexpressed G protein-coupled receptor; Prostate-specific G protein-coupled receptor 2 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 143503 |
| Human Swiss-Prot | Q8TCB6 |
| Source | Rabbit |
| Isotype | IgG |
| Target | D-GPCR |
| Fields | >>Olfactory transduction |
| Gene name | OR51E1 |
| Protein name | Olfactory receptor 51E1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human OR51E1. AA range:241-290 |
| Specificity | D-GPCR Polyclonal Antibody detects endogenous levels of D-GPCR protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 35kD |
| Background | Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008], |
| Function | function:Odorant receptor .,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Highly expressed in prostate. Very low levels may be detected in some other tissues, such as placenta, skeletal muscle, heart, ovary and testis. Up-regulated in prostate cancers., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . |
| Expression | Highly expressed in prostate. Very low levels may be detected in some other tissues, such as placenta, skeletal muscle, heart, ovary and testis. Up-regulated in prostate cancers. |
Additional Images
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Western Blot analysis of various cells using D-GPCR Polyclonal Antibody
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Immunofluorescence analysis of A549 cells, using OR51E1 Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from HeLa cells, using OR51E1 Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from K562 cells using OR51E1 antibody.
: AO-06-ES2167-50
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