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Antibody Product Overview
| ELK.No | ES2340 |
| Product name | FGF-22 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC;IF;ELISA |
| Other name | FGF22; Fibroblast growth factor 22; FGF-22 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 27006 |
| Human Swiss-Prot | Q9HCT0 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FGF-22 |
| Fields | >>MAPK signaling pathway;>>Ras signaling pathway;>>Rap1 signaling pathway;>>Calcium signaling pathway;>>PI3K-Akt signaling pathway;>>Regulation of actin cytoskeleton;>>Pathways in cancer;>>Chemical carcinogenesis - receptor activation;>>Melanoma;>>Breast cancer;>>Gastric cancer |
| Gene name | FGF22 |
| Protein name | Fibroblast growth factor 22 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 67112 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9ESS2 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FGF22. AA range:71-120 |
| Specificity | FGF-22 Polyclonal Antibody detects endogenous levels of FGF-22 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 20kD |
| Background | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014], |
| Function | function:May be involved in hair development.,similarity:Belongs to the heparin-binding growth factors family.,subunit:Interacts with FGFBP1., |
| Subcellular location | Secreted . |
| Expression | Placenta, |
Additional Images
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Western Blot analysis of various cells using FGF-22 Polyclonal Antibody diluted at 1:1000
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Immunofluorescence analysis of MCF7 cells, using FGF22 Antibody. The picture on the right is blocked with the synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human ovary tissue, using FGF22 Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from Jurkat and HT-29 cells, using FGF22 Antibody. The lane on the right is blocked with the synthesized peptide.
: AO-06-ES2340-50
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