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Antibody Product Overview
| ELK.No | ES2400 |
| Product name | Gasdermin C rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB IF;ELISA |
| Other name | GSDMC; MLZE; Gasdermin-C; Melanoma-derived leucine zipper-containing extranuclear factor |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 56169 |
| Human Swiss-Prot | Q9BYG8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Gasdermin C |
| Fields | |
| Gene name | GSDMC |
| Protein name | Gasdermin-C |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q99NB5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GSDMC. AA range:109-158 |
| Specificity | Gasdermin C Polyclonal Antibody detects endogenous levels of Gasdermin C protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 55kD |
| Background | caution:Despite its name, it is unclear if this protein contains a functional leucine zipper.,similarity:Belongs to the gasdermin family.,tissue specificity:Expressed primarily in trachea and spleen., |
| Function | caution:Despite its name, it is unclear if this protein contains a functional leucine zipper.,similarity:Belongs to the gasdermin family.,tissue specificity:Expressed primarily in trachea and spleen., |
| Subcellular location | [Gasdermin-C]: Cytoplasm, cytosol .; [Gasdermin-C, N-terminal]: Cell membrane ; Multi-pass membrane protein . |
| Expression | Expressed mainly in trachea and spleen (PubMed:11223543). In the esophagus, expressed in differentiating cells and probably in differentiated cells. Also detected in gastric epithelium (PubMed:19051310). |
Additional Images
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Immunofluorescence analysis of A549. 1,primary Antibody was diluted at 1:200(4°C overnight). 2, Goat Anti Rabbit IgG (H&L) - Alexa Fluor 488 Secondary antibody was diluted at 1:1000(room temperature, 50min).3, Picture B: DAPI(blue) 10min.
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Western Blot analysis of various cells using Gasdermin C Polyclonal Antibody diluted at 1:500
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Western blot analysis of GSDMC Antibody. The lane on the right is blocked with the GSDMC peptide.
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Western blot analysis of the lysates from HepG2 cells using GSDMC antibody.
: AO-06-ES2400-50
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