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Antibody Product Overview
| ELK.No | ES2441 |
| Product name | GNL1 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | GNL1; HSR1; Guanine nucleotide-binding protein-like 1; GTP-binding protein HSR1 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 2794 |
| Human Swiss-Prot | P36915 |
| Source | Rabbit |
| Isotype | IgG |
| Target | GNL1 |
| Fields | |
| Gene name | GNL1 |
| Protein name | Guanine nucleotide-binding protein-like 1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 14670 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P36916 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 309593 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q6MG06 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GNL1. AA range:61-110 |
| Specificity | GNL1 Polyclonal Antibody detects endogenous levels of GNL1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 69kD |
| Background | The GNL1 gene, identified in the human major histocompatibility complex class I region, shows a high degree of similarity with its mouse counterpart. The GNL1 gene is located less than 2 kb centromeric to HLA-E, in the same transcriptional orientation. GNL1 is telomeric to HLA-B and HLA-C. [provided by RefSeq, Jul 2008], |
| Function | domain:In contrast to other GTP-binding proteins, this family is characterized by a circular permutation of the GTPase motifs described by a G4-G1-G3 pattern.,function:Possible regulatory or functional link with the histocompatibility cluster.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the MMR1/HSR1 GTP-binding protein family., |
| Subcellular location | extracellular space,nucleus, |
| Expression | Cervix,Muscle,Peripheral blood leukocyte,Skin,T-cell, |
Additional Images
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Western Blot analysis of various cells using GNL1 Polyclonal Antibody
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Western Blot analysis of K562 cells using GNL1 Polyclonal Antibody
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Western blot analysis of lysates from Jurkat, LOVO, and K562 cells, using GNL1 Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES2441-100
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