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Antibody Product Overview
| ELK.No | ES2464 |
| Product name | GPR50 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IF;ELISA |
| Other name | GPR50; Melatonin-related receptor; G protein-coupled receptor 50; H9 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 9248 |
| Human Swiss-Prot | Q13585 |
| Source | Rabbit |
| Isotype | IgG |
| Target | GPR50 |
| Fields | >>Neuroactive ligand-receptor interaction |
| Gene name | GPR50 |
| Protein name | Melatonin-related receptor |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | O88495 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MTR1L. AA range:301-350 |
| Specificity | GPR50 Polyclonal Antibody detects endogenous levels of GPR50 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 68kD |
| Background | This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010], |
| Function | function:Does not bind melatonin.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Hypothalamus and pituitary., |
| Subcellular location | Cell membrane; Multi-pass membrane protein. |
| Expression | Hypothalamus and pituitary. |
Additional Images
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Western Blot analysis of various cells using GPR50 Polyclonal Antibody diluted at 1:1000
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Immunofluorescence analysis of LOVO cells, using MTR1L Antibody. The picture on the right is blocked with the synthesized peptide.
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: AO-06-ES2464-50
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