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Antibody Product Overview
| ELK.No | ES2555 |
| Product name | HORMAD1 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | HORMAD1; NOHMA; HORMA domain-containing protein 1; Cancer/testis antigen 46; CT46; Newborn ovary HORMA protein |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 84072 |
| Human Swiss-Prot | Q86X24 |
| Source | Rabbit |
| Isotype | IgG |
| Target | HORMAD1 |
| Fields | |
| Gene name | HORMAD1 |
| Protein name | HORMA domain-containing protein 1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q9D5T7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human HORMAD1. AA range:321-370 |
| Specificity | HORMAD1 Polyclonal Antibody detects endogenous levels of HORMAD1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 45kD |
| Background | This gene encodes a HORMA domain-containing protein. HORMA domains are involved in chromatin binding and play a role in cell cycle regulation. The encoded protein may play a role in meiosis, and expression of this gene is a potential marker for cancer. A pseudogene of this gene is located on the long arm of chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010], |
| Function | similarity:Contains 1 HORMA domain.,tissue specificity:Testis-specific. Over-expressed in carcinomas., |
| Subcellular location | Nucleus . Chromosome . Preferentially localizes to unsynapsed or desynapsed chromosomal regions during the prophase I stage of meiosis. TRIP13 is required for depletion from synapsed chromosomes. The expression of the phosphorylated form at Ser-377 is restricted to unsynapsed chromosomal regions (By similarity). . |
| Expression | Testis-specific. Over-expressed in carcinomas. |
Additional Images
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Western Blot analysis of various cells using HORMAD1 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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Western blot analysis of lysates from HeLa, HUVEC, and COLO cells, using HORMAD1 Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES2555-100
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