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Antibody Product Overview
| ELK.No | ES2592 |
| Product name | IFITM3 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IF;ELISA |
| Other name | IFITM3; Interferon-induced transmembrane protein 3; Dispanin subfamily A member 2b; DSPA2b; Interferon-inducible protein 1-8U |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 10410 |
| Human Swiss-Prot | Q01628 |
| Source | Rabbit |
| Isotype | IgG |
| Target | IFITM3 |
| Fields | |
| Gene name | IFITM3 |
| Protein name | Interferon-induced transmembrane protein 3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q9CQW9 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human IFM3. AA range:1-50 |
| Specificity | IFITM3 Polyclonal Antibody detects endogenous levels of IFITM3 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 15kD |
| Background | The protein encoded by this gene is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus, and dengue virus. Two transcript variants, only one of them protein-coding, have been found for this gene. Another variant encoding an N-terminally truncated isoform has been reported, but the full-length nature of this variant has not been determined. [provided by RefSeq, May 2012], |
| Function | induction:By alpha and gamma interferons.,similarity:Belongs to the CD225 family., |
| Subcellular location | Cell membrane ; Single-pass type II membrane protein . Late endosome membrane ; Single-pass type II membrane protein . Early endosome membrane ; Single-pass type II membrane protein. Lysosome membrane ; Single-pass type II membrane protein . Cytoplasm, perinuclear region . Co-localizes with BRI3 isoform 1 at the perinuclear region. . |
| Expression | Brain,Cervix,Vascular endothelial cell, |
Additional Images
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Western Blot analysis of various cells using IFITM3 Polyclonal Antibody diluted at 1:2000
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Western Blot analysis of HeLa cells using IFITM3 Polyclonal Antibody diluted at 1:2000
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Immunofluorescence analysis of MCF7 cells, using IFM3 Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from HepG2 and HeLa cells, using IFM3 Antibody. The lane on the right is blocked with the synthesized peptide.
: AO-06-ES2592-50
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