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Antibody Product Overview
| ELK.No | ES2633 |
| Product name | Integrin β5 rabbit pAb |
| Reactivity | Human;Mouse;Rat;Monkey |
| Applications | WB;ELISA |
| Other name | ITGB5; Integrin beta-5 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 3693 |
| Human Swiss-Prot | P18084 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Integrin β5 |
| Fields | >>Phagosome;>>PI3K-Akt signaling pathway;>>Focal adhesion;>>ECM-receptor interaction;>>Regulation of actin cytoskeleton;>>Human papillomavirus infection;>>Proteoglycans in cancer;>>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy |
| Gene name | ITGB5 |
| Protein name | Integrin beta-5 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 16419 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | O70309 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Integrin beta5. AA range:721-770 |
| Specificity | Integrin β5 Polyclonal Antibody detects endogenous levels of Integrin β5 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 88kD |
| Background | function:Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.,similarity:Belongs to the integrin beta chain family.,similarity:Contains 1 PSI domain.,similarity:Contains 1 VWFA domain.,subunit:Heterodimer of an alpha and a beta subunit. Beta-5 associates with alpha-V., |
| Function | function:Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.,similarity:Belongs to the integrin beta chain family.,similarity:Contains 1 PSI domain.,similarity:Contains 1 VWFA domain.,subunit:Heterodimer of an alpha and a beta subunit. Beta-5 associates with alpha-V., |
| Subcellular location | Membrane; Single-pass type I membrane protein. |
| Expression | Brain,Kidney,Thymic epithelium, |
Additional Images
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Western Blot analysis of various cells using Integrin β5 Polyclonal Antibody diluted at 1:1000
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Western Blot analysis of COS7 cells using Integrin β5 Polyclonal Antibody diluted at 1:1000
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Western blot analysis of lysates from COS7 cells, using Integrin beta5 Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES2633-100
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