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Antibody Product Overview
| ELK.No | ES2722 |
| Product name | LPAAT-δ rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC |
| Other name | AGPAT4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta; 1-acylglycerol-3-phosphate O-acyltransferase 4; 1-AGP acyltransferase 4; 1-AGPAT 4; Lysophosphatidic acid acyltransferase delta; LPAAT-delta |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 56895 |
| Human Swiss-Prot | Q9NRZ5 |
| Source | Rabbit |
| Isotype | IgG |
| Target | LPAAT-δ |
| Fields | >>Glycerolipid metabolism;>>Glycerophospholipid metabolism;>>Metabolic pathways;>>Phospholipase D signaling pathway |
| Gene name | AGPAT4 |
| Protein name | 1-acyl-sn-glycerol-3-phosphate acyltransferase delta |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 68262 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8K4X7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 170919 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q924S1 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human AGPAT4. AA range:151-200 |
| Specificity | LPAAT-δ Polyclonal Antibody detects endogenous levels of LPAAT-δ protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 44kD |
| Background | This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. [provided by RefSeq, Jul 2008], |
| Function | catalytic activity:Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate.,domain:The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.,function:Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.,pathway:Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3.,similarity:Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family., |
| Subcellular location | Endoplasmic reticulum membrane ; Multi-pass membrane protein . |
| Expression | Widely expressed with highest levels in skeletal muscle, followed by heart, liver, prostate and thymus. |
Additional Images
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Western Blot analysis of various cells using LPAAT-δ Polyclonal Antibody diluted at 1:500
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Western blot analysis of lysates from HeLa and MCF-7 cells, using AGPAT4 Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from HeLa cells using AGPAT4 antibody.
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Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
: AO-06-ES2722-50
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