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Antibody Product Overview
| ELK.No | ES2728 |
| Product name | L-type Ca++ CP γ7 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | CACNG7; Voltage-dependent calcium channel gamma-7 subunit; Neuronal voltage-gated calcium channel gamma-7 subunit; Transmembrane AMPAR regulatory protein gamma-7; TARP gamma-7 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 59284 |
| Human Swiss-Prot | P62955 |
| Source | Rabbit |
| Isotype | IgG |
| Target | L-type Ca++ CP γ7 |
| Fields | >>MAPK signaling pathway;>>Cardiac muscle contraction;>>Adrenergic signaling in cardiomyocytes;>>Oxytocin signaling pathway;>>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy |
| Gene name | CACNG7 |
| Protein name | Voltage-dependent calcium channel gamma-7 subunit |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 81904 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P62956 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 140728 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P62957 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CACNG7. AA range:198-247 |
| Specificity | L-type Ca++ CP γ7 Polyclonal Antibody detects endogenous levels of L-type Ca++ CP γ7 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 40kD |
| Background | calcium voltage-gated channel auxiliary subunit gamma 7(CACNG7) Homo sapiens The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010], |
| Function | function:Thought to stabilize the calcium channel in an inactivated (closed) state.,similarity:Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.,subunit:The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma.,tissue specificity:Widely expressed., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . |
| Expression | Detected in heart left ventricle (PubMed:21127204). Widely expressed. |
Additional Images
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Western Blot analysis of various cells using L-type Ca++ CP γ7 Polyclonal Antibody diluted at 1:1000
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Western blot analysis of lysates from HepG2 cells, using CACNG7 Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES2728-100
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