Français
English
Antibody Product Overview
| ELK.No | ES2730 |
| Product name | LTβR rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;IF;ELISA |
| Other name | LTBR; D12S370; TNFCR; TNFR3; TNFRSF3; Tumor necrosis factor receptor superfamily member 3; Lymphotoxin-beta receptor; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor type II |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 4055 |
| Human Swiss-Prot | P36941 |
| Source | Rabbit |
| Isotype | IgG |
| Target | LTβR |
| Fields | >>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>NF-kappa B signaling pathway;>>HIF-1 signaling pathway;>>Intestinal immune network for IgA production;>>Human T-cell leukemia virus 1 infection;>>Viral carcinogenesis |
| Gene name | LTBR |
| Protein name | Tumor necrosis factor receptor superfamily member 3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 17000 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P50284 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human LTBR. AA range:11-60 |
| Specificity | LTβR Polyclonal Antibody detects endogenous levels of LTβR protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 50kD |
| Background | lymphotoxin beta receptor(LTBR) Homo sapiens This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012], |
| Function | function:Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.,similarity:Contains 4 TNFR-Cys repeats.,subunit:Self-associates. Associates with TRAF3, TRAF4 and TRAF5. Interacts with HCV core protein., |
| Subcellular location | Membrane; Single-pass type I membrane protein. |
| Expression | Liver,Lung, |
Additional Images
No image
Western Blot analysis of various cells using LTβR Polyclonal Antibody
No image
Immunofluorescence analysis of HeLa cells, using LTBR Antibody. The picture on the right is blocked with the synthesized peptide.
No image
Western blot analysis of lysates from HeLa and HepG2 cells, using LTBR Antibody. The lane on the right is blocked with the synthesized peptide.
No image
: AO-06-ES2730-50
: 10 Items
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package