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Antibody Product Overview
| ELK.No | ES2881 |
| Product name | Myp rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC;IF;ELISA |
| Other name | Myp; NOL3; Nop30; Nucleolar protein 3; apoptosis repressor ARC; apoptosis repressor with CARD; apoptosis repressor with caspase recruitment domain (CARD); muscle-enriched cytoplasmic protein; nucleolar protein of 30 kDa |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 8996 |
| Human Swiss-Prot | O60936-2 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Myp |
| Fields | |
| Gene name | NOL3 |
| Protein name | Nucleolar protein 3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ARC. AA range:159-208 |
| Specificity | Myp Polyclonal Antibody detects endogenous levels of Myp protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 28kD |
| Background | NOL3 encodes an anti-apoptotic protein nucleolar protein 3 that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for NOL3. |
| Function | |
| Subcellular location | [Isoform 1]: Nucleus, nucleolus . The SR-rich C-terminus mediates nuclear localization. .; [Isoform 3]: Cytoplasm .; [Isoform 2]: Cytoplasm . Mitochondrion . Sarcoplasmic reticulum . Membrane ; Lipid-anchor . Phosphorylation at Thr-149 results in translocation to mitochondria. Colocalized with mitochondria in response to oxidative stress. . |
| Expression | Highly expressed in heart and skeletal muscle. Detected at low levels in placenta, liver, kidney and pancreas. |
Additional Images
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Western Blot analysis of various cells using Myp Polyclonal Antibody
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Immunohistochemistry analysis of paraffin-embedded human brain tissue, using ARC Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from HeLa cells, using ARC Antibody. The lane on the right is blocked with the synthesized peptide.
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Western Blot analysis of lane1 mouse-brain, lane2 mouse-kidney, lane3 Hela. land4 MCF7, lane5 293T, lane6 mouse-muscle using primary antibody at 1:1000 dilution 4°C, overnight. Secondary antibody(catalog#:RS23920) was diluted at 1:10000 25°C，1.5hours
: AO-06-ES2881-50
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