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Antibody Product Overview
| ELK.No | ES2931 |
| Product name | Neuroglycan C rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC |
| Other name | CSPG5; CALEB; NGC; Chondroitin sulfate proteoglycan 5; Acidic leucine-rich EGF-like domain-containing brain protein; Neuroglycan C |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 10675 |
| Human Swiss-Prot | O95196 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Neuroglycan C |
| Fields | |
| Gene name | CSPG5 |
| Protein name | Chondroitin sulfate proteoglycan 5 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 29873 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q71M36 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 50568 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q9ERQ6 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CSPG5. AA range:211-260 |
| Specificity | Neuroglycan C Polyclonal Antibody detects endogenous levels of Neuroglycan C protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 60kD |
| Background | The protein encoded by this gene is a proteoglycan that may function as a neural growth and differentiation factor. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011], |
| Function | developmental stage:Expressed in brain of 3 months, 5 and 10-year-old individuals.,function:May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation.,miscellaneous:Different forms of various molecular weight have been observed. Such forms are possibly due to different levels of glycosylation, phosphorylation and/or protein cleavage.,PTM:N-glycosylated.,PTM:O-glycosylated; contains chondroitin sulfate glycans. Part-time proteoglycan, expressed in part as a proteoglycan exhibiting chondroitin sulfate glycans and in part as a non-proteoglycan form. The relative amount of both forms depends on tissues and tissues maturation.,PTM:Phosphorylated; in intracellular and extracellular parts.,similarity:Contains 1 EGF-like domain.,subcellular location:In neurons, localizes to synaptic junctions (By similarity). Also detected in the endoplasmic reti |
| Subcellular location | Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse, synaptic cell membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Golgi apparatus membrane ; Single-pass type I membrane protein . Cell surface . In neurons, localizes to synaptic junctions. Also detected in the endoplasmic reticulum and the Golgi. Partially enriched in lipid rafts. . |
| Expression | Restricted to brain (at protein level). |
Additional Images
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Western Blot analysis of various cells using Neuroglycan C Polyclonal Antibody
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Western Blot analysis of HeLa cells using Neuroglycan C Polyclonal Antibody
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Western blot analysis of lysates from COLO and HeLa cells, using CSPG5 Antibody. The lane on the right is blocked with the synthesized peptide.
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Immunohistochemical analysis of paraffin-embedded human meningioma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
: AO-06-ES2931-50
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