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Antibody Product Overview
| ELK.No | ES2939 |
| Product name | NFRκB rabbit pAb |
| Reactivity | Human;Mouse;Monkey |
| Applications | WB; ELISA;IHC |
| Other name | NFRKB; INO80G; Nuclear factor related to kappa-B-binding protein; DNA-binding protein R kappa-B; INO80 complex subunit G |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 4798 |
| Human Swiss-Prot | Q6P4R8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | NFRκB |
| Fields | |
| Gene name | NFRKB |
| Protein name | Nuclear factor related to kappa-B-binding protein |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 235134 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q6PIJ4 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NFRKB. AA range:463-512 |
| Specificity | NFRκB Polyclonal Antibody detects endogenous levels of NFRκB protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 110kD |
| Background | function:Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subunit:Component of the chromatin-remodeling INO80 complex, at least composed of ACTL6A, ACTR5, ACTR8, RVBL1, RVBL2, INO80, INO80B, INO80C, INO80D and INO80E.,tissue specificity:Expressed in thymus, brain, testes, spleen and liver., |
| Function | function:Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subunit:Component of the chromatin-remodeling INO80 complex, at least composed of ACTL6A, ACTR5, ACTR8, RVBL1, RVBL2, INO80, INO80B, INO80C, INO80D and INO80E.,tissue specificity:Expressed in thymus, brain, testes, spleen and liver., |
| Subcellular location | Nucleus . |
| Expression | Expressed in thymus, brain, testes, spleen and liver. |
Additional Images
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Western Blot analysis of various cells using NFRκB Polyclonal Antibody diluted at 1:500 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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Western Blot analysis of COS7 cells using NFRκB Polyclonal Antibody diluted at 1:500 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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Western blot analysis of lysates from COS7 cells, using NFRKB Antibody. The lane on the right is blocked with the synthesized peptide.
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
: AO-06-ES2939-50
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