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Antibody Product Overview
| ELK.No | ES2981 |
| Product name | NPY2-R rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IF;ELISA |
| Other name | NPY2R; Neuropeptide Y receptor type 2; NPY2-R; NPY-Y2 receptor; Y2 receptor |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 4887 |
| Human Swiss-Prot | P49146 |
| Source | Rabbit |
| Isotype | IgG |
| Target | NPY2-R |
| Fields | >>Neuroactive ligand-receptor interaction |
| Gene name | NPY2R |
| Protein name | Neuropeptide Y receptor type 2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P97295 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NPY2R. AA range:1-50 |
| Specificity | NPY2-R Polyclonal Antibody detects endogenous levels of NPY2-R protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 43kD |
| Background | function:Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra., |
| Function | function:Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra., |
| Subcellular location | Cell membrane; Multi-pass membrane protein. |
| Expression | High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra. |
Additional Images
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Western Blot analysis of various cells using NPY2-R Polyclonal Antibody diluted at 1:500
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Western Blot analysis of HT29 cells using NPY2-R Polyclonal Antibody diluted at 1:500
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Immunofluorescence analysis of A549 cells, using NPY2R Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from HepG2 cells, using NPY2R Antibody. The lane on the right is blocked with the synthesized peptide.
: AO-06-ES2981-50
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