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Antibody Product Overview
| ELK.No | ES2982 |
| Product name | NPY5-R rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC;IF;ELISA |
| Other name | NPY5R; NPYR5; Neuropeptide Y receptor type 5; NPY5-R; NPY-Y5 receptor; NPYY5-R; Y5 receptor |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 4889 |
| Human Swiss-Prot | Q15761 |
| Source | Rabbit |
| Isotype | IgG |
| Target | NPY5-R |
| Fields | >>Neuroactive ligand-receptor interaction |
| Gene name | NPY5R |
| Protein name | Neuropeptide Y receptor type 5 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 18168 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | O70342 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 25340 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q63634 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NPY5R. AA range:221-270 |
| Specificity | NPY5-R Polyclonal Antibody detects endogenous levels of NPY5-R protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 48kD |
| Background | The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2015], |
| Function | function:Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Brain; hypothalamus., |
| Subcellular location | Cell membrane; Multi-pass membrane protein. |
| Expression | Brain; hypothalamus. |
Additional Images
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Western Blot analysis of various cells using NPY5-R Polyclonal Antibody
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Immunofluorescence analysis of A549 cells, using NPY5R Antibody. The picture on the right is blocked with the synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using NPY5R Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from COLO, Jurkat, and HepG2 cells, using NPY5R Antibody. The lane on the right is blocked with the synthesized peptide.
: AO-06-ES2982-50
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