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Antibody Product Overview
| ELK.No | ES3002 |
| Product name | OCT3 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | SLC22A3; EMTH; OCT3; Solute carrier family 22 member 3; Extraneuronal monoamine transporter; EMT; Organic cation transporter 3 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 6581 |
| Human Swiss-Prot | O75751 |
| Source | Rabbit |
| Isotype | IgG |
| Target | OCT3 |
| Fields | >>Choline metabolism in cancer |
| Gene name | SLC22A3 |
| Protein name | Solute carrier family 22 member 3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q9WTW5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SLC22A3. AA range:275-324 |
| Specificity | OCT3 Polyclonal Antibody detects endogenous levels of 40819 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 61kD |
| Background | Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. [provided by RefSeq, Jul 2008], |
| Function | function:Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain.,similarity:Belongs to the major facilitator superfamily. Organic cation transporter family.,tissue specificity:Expressed in placenta, skeletal muscle, prostate, aorta, liver, fetal lung, salivary gland, adrenal gland, kidney and brain cortex. No expression detected in spleen., |
| Subcellular location | Membrane; Multi-pass membrane protein. |
| Expression | Expressed in placenta, skeletal muscle, prostate, aorta, liver, fetal lung, salivary gland, adrenal gland, kidney and brain cortex. No expression detected in spleen. |
Additional Images
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Western Blot analysis of various cells using OCT3 Polyclonal Antibody
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Western blot analysis of lysates from HUVEC, COLO, and HT-29 cells, using SLC22A3 Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES3002-50
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