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Antibody Product Overview
| ELK.No | ES3238 |
| Product name | PMEPA1 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC;IF;ELISA |
| Other name | PMEPA1; STAG1; TMEPAI; Transmembrane prostate androgen-induced protein; Solid tumor-associated 1 protein |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 56937 |
| Human Swiss-Prot | Q969W9 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PMEPA1 |
| Fields | |
| Gene name | PMEPA1 |
| Protein name | Transmembrane prostate androgen-induced protein |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q9D7R2 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TMEPA. AA range:101-150 |
| Specificity | PMEPA1 Polyclonal Antibody detects endogenous levels of PMEPA1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 37kD |
| Background | This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011], |
| Function | domain:The WW-binding motifs mediate interaction with NEDD4.,induction:By androgen.,similarity:Belongs to the PMEPA1 family.,subunit:Interacts with the WW domains of NEDD4.,tissue specificity:Highest expression in prostate. Also expressed in ovary., |
| Subcellular location | Early endosome membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. |
| Expression | Highest expression in prostate. Also expressed in ovary. |
Additional Images
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Western Blot analysis of various cells using PMEPA1 Polyclonal Antibody diluted at 1:500
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Western Blot analysis of HT29 cells using PMEPA1 Polyclonal Antibody diluted at 1:500
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Immunofluorescence analysis of HUVEC cells, using TMEPA Antibody. The picture on the right is blocked with the synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human prostate tissue, using TMEPA Antibody. The picture on the right is blocked with the synthesized peptide.
: AO-06-ES3238-50
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