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Antibody Product Overview
| ELK.No | ES3335 |
| Product name | RCL rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC |
| Other name | RCL; C6orf108; Deoxyribonucleoside 5'-monophosphate N-glycosidase; c-Myc-responsive protein Rcl |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 10591 |
| Human Swiss-Prot | O43598 |
| Source | Rabbit |
| Isotype | IgG |
| Target | RCL |
| Fields | |
| Gene name | RCL |
| Protein name | Deoxyribonucleoside 5'-monophosphate N-glycosidase |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q80VJ3 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RCL. AA range:1-50 |
| Specificity | RCL Polyclonal Antibody detects endogenous levels of RCL protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 22kD |
| Background | This gene was identified on the basis of its stimulation by c-Myc protein. The latter is a transcription factor that participates in the regulation of cell proliferation, differentiation, and apoptosis. The exact function of this gene is not known but studies in rat suggest a role in cellular proliferation and c-Myc-mediated transformation. Two alternative transcripts encoding different proteins have been described. [provided by RefSeq, Jul 2008], |
| Function | caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:May play a role during cellular proliferation and c-Myc-mediated transformation.,tissue specificity:Expression is elevated in lymphoid cells that overexpress c-Myc., |
| Subcellular location | Cytoplasm . Nucleus . |
| Expression | Expressed at low levels in brain, colon, lung, peripheral blood leukocytes, placenta, small intestine, and thymus. Expressed at high levels in heart, kidney, liver, skeletal muscle and spleen. Overexpressed in a significant proportion of breast cancers. |
Additional Images
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Western Blot analysis of various cells using RCL Polyclonal Antibody
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Western blot analysis of lysates from Jurkat and K562 cells, using RCL Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from 293 cells using RCL antibody.
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Immunohistochemical analysis of paraffin-embedded human uterus. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
: AO-06-ES3335-100
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