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Antibody Product Overview
| ELK.No | ES3386 |
| Product name | RNF130 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA;IHC |
| Other name | RNF130; E3 ubiquitin-protein ligase RNF130; Goliath homolog; H-Goliath; RING finger protein 130 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 55819 |
| Human Swiss-Prot | Q86XS8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | RNF130 |
| Fields | |
| Gene name | RNF130 |
| Protein name | E3 ubiquitin-protein ligase RNF130 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 59044 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8VEM1 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 652955 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q6Y290 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RNF130. AA range:231-280 |
| Specificity | RNF130 Polyclonal Antibody detects endogenous levels of RNF130 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 36kD |
| Background | ring finger protein 130(RNF130) Homo sapiens The protein encoded by this gene contains a RING finger motif and is similar to g1, a Drosophila zinc-finger protein that is expressed in mesoderm and involved in embryonic development. The expression of the mouse counterpart was found to be upregulated in myeloblastic cells following IL3 deprivation, suggesting that this gene may regulate growth factor withdrawal-induced apoptosis of myeloid precursor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013], |
| Function | function:May have a role during the programmed cell death of hematopoietic cells.,similarity:Contains 1 PA (protease associated) domain.,similarity:Contains 1 RING-type zinc finger., |
| Subcellular location | Membrane ; Single-pass type I membrane protein . Cytoplasm . |
| Expression | Ubiquitously expressed. Highly expressed in leukocytes. Not expressed in erythroblasts. |
Additional Images
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Western Blot analysis of various cells using RNF130 Polyclonal Antibody diluted at 1:1000
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Western blot analysis of lysates from HeLa, Jurkat, HUVEC, and MCF-7 cells, using RNF130 Antibody. The lane on the right is blocked with the synthesized peptide.
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Immunohistochemical analysis of paraffin-embedded human cervical carcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES3386-50
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