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Antibody Product Overview
| ELK.No | ES3480 |
| Product name | Sox-8/9/17/18 rabbit pAb |
| Reactivity | Human;Mouse;Monkey |
| Applications | WB;IHC;IF;ELISA |
| Other name | SOX8; Transcription factor SOX-8; SOX9; Transcription factor SOX-9; SOX17; Transcription factor SOX-17; SOX18; Transcription factor SOX-18 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 30812/6662/64321/54345 |
| Human Swiss-Prot | P57073/P48436/Q9H6I2/P35713 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Sox-8/9/17/18 |
| Fields | |
| Gene name | SOX8/9/17/18 |
| Protein name | Transcription factor SOX-8/9/17/18 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 20681/20682/20671/20672 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SOX8/9/17/18. AA range:116-165 |
| Specificity | Sox-8/9/17/18 Polyclonal Antibody detects endogenous levels of Sox-8/9/17/18 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 47kD |
| Background | SRY-box 8(SOX8) Homo sapiens This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome). [provided by RefSeq, Jul 2008], |
| Function | function:May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'.,similarity:Contains 1 HMG box DNA-binding domain., |
| Subcellular location | Nucleus . |
| Expression | Brain,Spleen, |
Additional Images
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Western Blot analysis of various cells using Sox-8/9/17/18 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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Immunohistochemistry analysis of paraffin-embedded human brain tissue, using SOX8/9/17/18 Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from COS7 cells, treated with serum 10% 30', using SOX8/9/17/18 Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from HeLa cells using SOX8/9/17/18 antibody.
: AO-06-ES3480-100
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