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Antibody Product Overview
| ELK.No | ES3521 |
| Product name | STEAP1 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC;IF;ELISA |
| Other name | STEAP1; PRSS24; STEAP; Metalloreductase STEAP1; Six-transmembrane epithelial antigen of prostate 1 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 26872 |
| Human Swiss-Prot | Q9UHE8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | STEAP1 |
| Fields | >>Mineral absorption |
| Gene name | STEAP1 |
| Protein name | Metalloreductase STEAP1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q9CWR7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human STEAP1. AA range:31-80 |
| Specificity | STEAP1 Polyclonal Antibody detects endogenous levels of STEAP1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 36kD |
| Background | This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions. [provided by RefSeq, Jul 2008], |
| Function | cofactor:FAD.,function:Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor.,similarity:Belongs to the STEAP family.,similarity:Contains 1 ferric oxidoreductase domain.,tissue specificity:Ubiquitously expressed. Highly expressed in prostate tumors., |
| Subcellular location | Endosome membrane ; Multi-pass membrane protein . |
| Expression | Ubiquitously expressed. Highly expressed in prostate tumors. |
Additional Images
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Western Blot analysis of various cells using STEAP1 Polyclonal Antibody
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Immunohistochemical analysis of paraffin-embedded Human prostate cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
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Immunohistochemistry analysis of STEAP1 antibody in paraffin-embedded human prostate carcinoma tissue.
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Western blot analysis of lysate from A549, using STEAP1 antibody.
: AO-06-ES3521-100
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