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Antibody Product Overview
| ELK.No | ES3549 |
| Product name | TAB182 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;ELISA |
| Other name | TNKS1BP1; KIAA1741; TAB182; 182 kDa tankyrase-1-binding protein |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 85456 |
| Human Swiss-Prot | Q9C0C2 |
| Source | Rabbit |
| Isotype | IgG |
| Target | TAB182 |
| Fields | |
| Gene name | TNKS1BP1 |
| Protein name | 182 kDa tankyrase-1-binding protein |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 228140 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P58871 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TNKS1BP1. AA range:1601-1650 |
| Specificity | TAB182 Polyclonal Antibody detects endogenous levels of TAB182 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 150kD |
| Background | PTM:ADP-ribosylated by TNKS1 (in vitro).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin.,subunit:Binds to the ANK repeat domain of TNKS1 and TNKS2.,tissue specificity:Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes., |
| Function | PTM:ADP-ribosylated by TNKS1 (in vitro).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin.,subunit:Binds to the ANK repeat domain of TNKS1 and TNKS2.,tissue specificity:Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes., |
| Subcellular location | Nucleus. Cytoplasm, cytoskeleton. Chromosome. Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin. |
| Expression | Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes. |
Additional Images
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Western Blot analysis of various cells using TAB182 Polyclonal Antibody diluted at 1:1000
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Western blot analysis of lysates from 293 cells, using TNKS1BP1 Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES3549-50
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