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Antibody Product Overview
| ELK.No | ES3577 |
| Product name | TDE1 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC;IF;ELISA |
| Other name | SERINC3; DIFF33; TDE1; SBBI99; Serine incorporator 3; Tumor differentially expressed protein 1 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 10955 |
| Human Swiss-Prot | Q13530 |
| Source | Rabbit |
| Isotype | IgG |
| Target | TDE1 |
| Fields | >>Viral life cycle - HIV-1 |
| Gene name | SERINC3 |
| Protein name | Serine incorporator 3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 26943 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9QZI9 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SERC3. AA range:361-410 |
| Specificity | TDE1 Polyclonal Antibody detects endogenous levels of TDE1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 52kD |
| Background | function:May be involved in cellular transformation.,PTM:N-glycosylated.,similarity:Belongs to the TDE1 family.,tissue specificity:Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues., |
| Function | function:May be involved in cellular transformation.,PTM:N-glycosylated.,similarity:Belongs to the TDE1 family.,tissue specificity:Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein .; Cytoplasm, perinuclear region . (Microbial infection) Upon HIV-1 infection, it is redirected to perinuclear region following interaction with HIV-1 Nef, excluding it from virions particles, thereby preventing subsequent antiviral defense activity (Probable). . |
| Expression | Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues. |
Additional Images
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Western Blot analysis of various cells using TDE1 Polyclonal Antibody
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Immunofluorescence analysis of HepG2 cells, using SERC3 Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from 293 cells, using SERC3 Antibody. The lane on the right is blocked with the synthesized peptide.
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Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
: AO-06-ES3577-100
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