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Antibody Product Overview
| ELK.No | ES3758 |
| Product name | EEA1 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;ELISA |
| Other name | EEA1; ZFYVE2; Early endosome antigen 1; Endosome-associated protein p162; Zinc finger FYVE domain-containing protein 2 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 8411 |
| Human Swiss-Prot | Q15075 |
| Source | Rabbit |
| Isotype | IgG |
| Target | EEA1 |
| Fields | >>Endocytosis;>>Phagosome;>>Tuberculosis |
| Gene name | EEA1 |
| Protein name | Early endosome antigen 1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 216238 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BL66 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human EEA1. AA range:205-254 |
| Specificity | EEA1 Polyclonal Antibody detects endogenous levels of EEA1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 162kD |
| Background | disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.,domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate.,function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 FYVE-type zinc finger.,subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding., |
| Function | disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.,domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate.,function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 FYVE-type zinc finger.,subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding., |
| Subcellular location | Cytoplasm. Early endosome membrane; Peripheral membrane protein. |
| Expression | Aorta,Cervix carcinoma,Fetal brain cortex,Skeletal muscle, |
Additional Images
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Western Blot analysis of extracts from K562 cells, using EEA1 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Western blot analysis of lysates from A431 cells , using EEA1 antibody.
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: AO-06-ES3758-100
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