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Antibody Product Overview
| ELK.No | ES3791 |
| Product name | BAGE5 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | BAG5; KIAA0873; BAG family molecular chaperone regulator 5; BAG-5; Bcl-2-associated athanogene 5 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 9529 |
| Human Swiss-Prot | Q9UL15 |
| Source | Rabbit |
| Isotype | IgG |
| Target | BAGE5 |
| Fields | |
| Gene name | BAG5 |
| Protein name | BAG family molecular chaperone regulator 5 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 70369 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8CI32 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 366734 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q5QJC9 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from BAGE5 . at AA range: 30-110 |
| Specificity | BAGE5 Polyclonal Antibody detects endogenous levels of BAGE5 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 51kD |
| Background | The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
| Function | function:Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2.,similarity:Contains 4 BAG domains.,subunit:Binds to the ATPase domain of HSP70/HSC chaperones. Binds PARK2., |
| Subcellular location | nucleus,mitochondrion,cytosol,membrane,inclusion body,perinuclear region of cytoplasm, |
| Expression | Brain, |
Additional Images
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Western Blot analysis of extracts from Jurkat, K562 cells, using BAGE5 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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: AO-06-ES3791-50
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