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Antibody Product Overview
| ELK.No | ES3810 |
| Product name | UBE4A rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC;IF;ELISA |
| Other name | UBE4A; KIAA0126; Ubiquitin conjugation factor E4 A |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 9354 |
| Human Swiss-Prot | Q14139 |
| Source | Rabbit |
| Isotype | IgG |
| Target | UBE4A |
| Fields | >>Ubiquitin mediated proteolysis |
| Gene name | UBE4A |
| Protein name | Ubiquitin conjugation factor E4 A |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | 315608 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q6P7A2 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from the N-terminal region of human UBE4A. |
| Specificity | UBE4A Polyclonal Antibody detects endogenous levels of UBE4A protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 122kD |
| Background | This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011], |
| Function | function:Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the ubiquitin conjugation factor E4 family.,similarity:Contains 1 U-box domain., |
| Subcellular location | Cytoplasm . |
| Expression | Bone marrow,Platelet,Skeletal muscle, |
Additional Images
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Western Blot analysis of extracts from Jurkat cells, using UBE4A Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Immunohistochemical analysis of paraffin-embedded rat-muscle, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded rat-muscle, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded mouse-muscle, antibody was diluted at 1:100
: AO-06-ES3810-100
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