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Antibody Product Overview
| ELK.No | ES3880 |
| Product name | Eotaxin-3 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC;IF;ELISA |
| Other name | CCL26; SCYA26; C-C motif chemokine 26; CC chemokine IMAC; Eotaxin-3; Macrophage inflammatory protein 4-alpha; MIP-4-alpha; Small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 10344 |
| Human Swiss-Prot | Q9Y258 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Eotaxin-3 |
| Fields | >>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>Chemokine signaling pathway |
| Gene name | CCL26 |
| Protein name | C-C motif chemokine 26 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human CCL26. AA range:31-80 |
| Specificity | Eotaxin-3 Polyclonal Antibody detects endogenous levels of Eotaxin-3 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 12kD |
| Background | This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2008], |
| Function | function:Chemotactic for eosinophils and basophils. Binds to CCR3.,online information:CCL26 entry,similarity:Belongs to the intercrine beta (chemokine CC) family.,subunit:Monomer.,tissue specificity:Ubiquitously expressed at low levels in various tissues including heart and ovary., |
| Subcellular location | Secreted . |
| Expression | Ubiquitously expressed at low levels in various tissues including heart and ovary. |
Additional Images
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Western Blot analysis of PC-3, A549, OVCAR3, mouse colon cells using Eotaxin-3 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100
: AO-06-ES3880-50
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