Français
English
Antibody Product Overview
| ELK.No | ES3887 |
| Product name | ALDH1A1 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC;IF;ELISA |
| Other name | ALDH1A1; ALDC; ALDH1; PUMB1; Retinal dehydrogenase 1; RALDH 1; RalDH1; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 216 |
| Human Swiss-Prot | P00352 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ALDH1A1 |
| Fields | >>Retinol metabolism;>>Metabolic pathways |
| Gene name | ALDH1A1 |
| Protein name | Retinal dehydrogenase 1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P24549 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the N-terminal region of human ALDH1A1. AA range:21-70 |
| Specificity | ALDH1A1 Polyclonal Antibody detects endogenous levels of ALDH1A1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 55kD |
| Background | The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011], |
| Function | catalytic activity:Retinal + NAD(+) + H(2)O = retinoate + NADH.,function:Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid.,pathway:Cofactor metabolism; retinol metabolism.,similarity:Belongs to the aldehyde dehydrogenase family.,subunit:Homotetramer., |
| Subcellular location | Cytoplasm, cytosol . Cell projection, axon . |
| Expression | Expressed by erythrocytes (at protein level). |
Additional Images
No image
Western Blot analysis of mouse lung, mouse liver cells using ALDH1A1 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
No image
Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
No image
Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
No image
Western blot analysis of lysate from mouse lung, using ALDH1A1 Antibody.
: AO-06-ES3887-100
: 10 Items
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package