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Antibody Product Overview
| ELK.No | ES3914 |
| Product name | Aldolase C rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC;IF;ELISA |
| Other name | ALDOC; ALDC; Fructose-bisphosphate aldolase C; Brain-type aldolase |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 230 |
| Human Swiss-Prot | P09972 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Aldolase C |
| Fields | >>Glycolysis / Gluconeogenesis;>>Pentose phosphate pathway;>>Fructose and mannose metabolism;>>Metabolic pathways;>>Carbon metabolism;>>Biosynthesis of amino acids;>>HIF-1 signaling pathway |
| Gene name | ALDOC |
| Protein name | Fructose-bisphosphate aldolase C |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 11676 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P05063 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 24191 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P09117 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from the N-terminal region of human ALDOC. AA range:21-70 |
| Specificity | Aldolase C Polyclonal Antibody detects endogenous levels of Aldolase C protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 39kD |
| Background | This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008], |
| Function | catalytic activity:D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.,miscellaneous:In vertebrates, three forms of this ubiquitous glycolytic enzyme are found, aldolase A in muscle, aldolase B in liver and aldolase C in brain.,pathway:Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.,similarity:Belongs to the class I fructose-bisphosphate aldolase family.,subunit:Homotetramer., |
| Subcellular location | mitochondrion,cytosol,cytoskeleton,extracellular exosome, |
| Expression | Brain,Colon,Epithelium,Eye,Uterus, |
Additional Images
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Western Blot analysis of mouse liver, mouse spinal cord cells using Aldolase C Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100
: AO-06-ES3914-50
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