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Antibody Product Overview
| ELK.No | ES3926 |
| Product name | CRP rabbit pAb |
| Reactivity | Human;Rat |
| Applications | WB;IHC;IF;ELISA |
| Other name | CRP; PTX1; C-reactive protein |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 1401 |
| Human Swiss-Prot | P02741 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CRP |
| Fields | |
| Gene name | CRP |
| Protein name | C-reactive protein |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P14847 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 25419 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P48199 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human CRP. AA range:101-150 |
| Specificity | CRP Polyclonal Antibody detects endogenous levels of CRP protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 25kD |
| Background | C-reactive protein(CRP) Homo sapiens The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009], |
| Function | cofactor:Binds 2 calcium ions per subunit.,function:Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.,induction:The concentration of CRP in plasma increases greatly during acute phase response to tissue injury, infection or other inflammatory stimuli. It is induced by IL-1 and IL-6.,mass spectrometry: Ref.14,miscellaneous:This protein owes its name to its ability precipitate pneumococcal C-polysaccharide in the presence of calcium.,online information:C-reactive protein entry,online information:No more Christmas pudding? - Issue 30 of January 2003,similarity:Belongs to the pentaxin family.,similarity:Contains 1 pentaxin dom |
| Subcellular location | Secreted. |
| Expression | Found in plasma. |
Additional Images
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Western Blot analysis of mouse liver cells using CRP Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded rat-liver, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded rat-liver, antibody was diluted at 1:100
: AO-06-ES3926-50
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