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Antibody Product Overview
| ELK.No | ES3955 |
| Product name | HDC rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC;IF;ELISA |
| Other name | HDC; Histidine decarboxylase; HDC |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 3067 |
| Human Swiss-Prot | P19113 |
| Source | Rabbit |
| Isotype | IgG |
| Target | HDC |
| Fields | >>Histidine metabolism;>>Metabolic pathways |
| Gene name | HDC |
| Protein name | Histidine decarboxylase |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 15186 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P23738 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | P16453 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human HDC. AA range:201-250 |
| Specificity | HDC Polyclonal Antibody detects endogenous levels of HDC protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 72kD |
| Background | This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.[provided by RefSeq, Aug 2010], |
| Function | catalytic activity:L-histidine = histamine + CO(2).,cofactor:Pyridoxal phosphate.,pathway:Amine and polyamine biosynthesis; histamine biosynthesis; histamine from L-histidine: step 1/1.,similarity:Belongs to the group II decarboxylase family.,subunit:Homodimer., |
| Subcellular location | cytosol, |
| Expression | Leukemia, |
Additional Images
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Western Blot analysis of K562 cells using HDC Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100
: AO-06-ES3955-100
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