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Antibody Product Overview
| ELK.No | ES3971 |
| Product name | CD2 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC;IF;ELISA |
| Other name | CD2; SRBC; T-cell surface antigen CD2; Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; CD2 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 914 |
| Human Swiss-Prot | P06729 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CD2 |
| Fields | >>Cell adhesion molecules;>>Hematopoietic cell lineage |
| Gene name | CD2 |
| Protein name | T-cell surface antigen CD2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P08920 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the N-terminal region of human CD2. AA range:31-80 |
| Specificity | CD2 Polyclonal Antibody detects endogenous levels of CD2 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 39kD |
| Background | The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016], |
| Function | function:CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.,online information:CD2 entry,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with CD2AP (By similarity). Interacts with PSTPIP1., |
| Subcellular location | Cell membrane ; Single-pass type I membrane protein . |
| Expression | Expressed in natural killer cells (at protein level). |
Additional Images
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Western Blot analysis of K562 cells using CD2 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Immunohistochemical analysis of paraffin-embedded human-pancreas, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded human-pancreas, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded human-pancreas, antibody was diluted at 1:100
: AO-06-ES3971-50
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