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Antibody Product Overview
| ELK.No | ES4025 |
| Product name | PSP rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA;IHC |
| Other name | PSPN; Persephin; PSP |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 5623 |
| Human Swiss-Prot | O60542 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PSP |
| Fields | |
| Gene name | PSPN |
| Protein name | Persephin |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | O70300 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 25525 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | O70301 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from the C-terminal region of human PSPN. AA range:101-150 |
| Specificity | PSP Polyclonal Antibody detects endogenous levels of PSP protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 16kD |
| Background | persephin(PSPN) Homo sapiens This gene encodes a secreted ligand of the GDNF (glial cell line-derived neurotrophic factor) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. This protein may play a role in cell death, and nervous system development and function. Elevated expression of this gene has been observed in oral squamous cell carcinoma. [provided by RefSeq, Aug 2016], |
| Function | function:Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons.,similarity:Belongs to the TGF-beta family. GDNF subfamily.,subunit:Homodimer; disulfide-linked., |
| Subcellular location | Secreted. |
| Expression |
Additional Images
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Western Blot analysis of 293 cells using PSP Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Western blot analysis of lysate from 293 cells, using PSPN Antibody.
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES4025-50
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