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Antibody Product Overview
| ELK.No | ES4060 |
| Product name | KLF13 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;IHC;IF;ELISA |
| Other name | KLF13; BTEB3; NSLP1; Krueppel-like factor 13; Basic transcription element-binding protein 3; BTE-binding protein 3; Novel Sp1-like zinc finger transcription factor 1;RANTES factor of late activated T-lymphocytes 1; RFLAT-1; Transcription factor BTEB3; Transcription factor NSLP1 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 51621 |
| Human Swiss-Prot | Q9Y2Y9 |
| Source | Rabbit |
| Isotype | IgG |
| Target | KLF13 |
| Fields | |
| Gene name | KLF13 |
| Protein name | Krueppel-like factor 13 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 50794 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9JJZ6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human KLF13 around the non-acetylation site of Lys166. AA range:131-180 |
| Specificity | KLF13 Polyclonal Antibody detects endogenous levels of KLF13 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 31kD |
| Background | KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).[supplied by OMIM, Mar 2008], |
| Function | domain:The Ala/Pro-rich domain may contain discrete activation and repression subdomains and also can mediate protein-protein interactions.,function:Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells.,PTM:Phosphorylated.,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,tissue specificity:Ubiquitous., |
| Subcellular location | Nucleus. |
| Expression | Ubiquitous. |
Additional Images
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Western Blot analysis of L929 cells using KLF13 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded human-pancreas, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded human-pancreas, antibody was diluted at 1:100
: AO-06-ES4060-50
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