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Antibody Product Overview
| ELK.No | ES4118 |
| Product name | Glut5 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | SLC2A5; GLUT5; Solute carrier family 2, facilitated glucose transporter member 5; Fructose transporter; Glucose transporter type 5, small intestine; GLUT-5 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 6518 |
| Human Swiss-Prot | P22732 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Glut5 |
| Fields | >>Carbohydrate digestion and absorption |
| Gene name | SLC2A5 |
| Protein name | Solute carrier family 2 facilitated glucose transporter member 5 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q9WV38 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the N-terminal region of human SLC2A5. AA range:31-80 |
| Specificity | Glut5 Polyclonal Antibody detects endogenous levels of Glut5 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 55kD |
| Background | The protein encoded by this gene is a fructose transporter responsible for fructose uptake by the small intestine. The encoded protein also is necessary for the increase in blood pressure due to high dietary fructose consumption. [provided by RefSeq, Jun 2016], |
| Function | function:Cytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter.,induction:By forskolin (in Caco-2 cells).,mass spectrometry: PubMed:11840567,similarity:Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.,tissue specificity:Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue., |
| Subcellular location | Apical cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cell membrane, sarcolemma . Localized on the apical membrane of jejunum villi, but also on lateral plasma membranes of the villi. Transport to the cell membrane is dependent on RAB11A. . |
| Expression | Detected in skeletal muscle, and in jejunum brush border membrane and basolateral membrane (at protein level) (PubMed:7619085). Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue. |
Additional Images
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Western Blot analysis of K562 cells using Glut5 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Western blot analysis of lysate from K562 cells, using SLC2A5 Antibody.
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: AO-06-ES4118-100
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