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Antibody Product Overview
| ELK.No | ES4140 |
| Product name | Cerberus rabbit pAb |
| Reactivity | Human;Rat |
| Applications | WB;IHC;IF;ELISA |
| Other name | CER1; DAND4; Cerberus; Cerberus-related protein; DAN domain family member 4 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 9350 |
| Human Swiss-Prot | O95813 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Cerberus |
| Fields | >>Wnt signaling pathway |
| Gene name | CER1 |
| Protein name | Cerberus |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 12622 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | O55233 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human CER1. AA range:91-140 |
| Specificity | Cerberus Polyclonal Antibody detects endogenous levels of Cerberus protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 30kD |
| Background | This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. [provided by RefSeq, Jul 2008], |
| Function | function:Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak.,PTM:N-glycosylated.,sequence caution:Translated as Ser.,similarity:Belongs to the DAN family.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,subunit:Forms monomers and predominantly dimers., |
| Subcellular location | Secreted . |
| Expression | Blood,PCR rescued clones, |
Additional Images
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Western Blot analysis of MCF-7 cells using Cerberus Polyclonal Antibody. Antibody was diluted at 1:500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:100
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Western Blot analysis of Rat-heart Rat-brain using Cerberus Polyclonal Antibody diluted at 1:500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
: AO-06-ES4140-50
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