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Antibody Product Overview
| ELK.No | ES4200 |
| Product name | IL-1RII rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC;IF;ELISA |
| Other name | IL1R2; IL1RB; Interleukin-1 receptor type 2; IL-1R-2; IL-1RT-2; IL-1RT2; CD121 antigen-like family member B; CDw121b; IL-1 type II receptor; Interleukin-1 receptor beta; IL-1R-beta; Interleukin-1 receptor type II; CD121b |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 7850 |
| Human Swiss-Prot | P27930 |
| Source | Rabbit |
| Isotype | IgG |
| Target | IL-1RII |
| Fields | >>Cytokine-cytokine receptor interaction;>>Hematopoietic cell lineage;>>Amoebiasis;>>Human T-cell leukemia virus 1 infection;>>Transcriptional misregulation in cancer;>>Prostate cancer;>>Fluid shear stress and atherosclerosis |
| Gene name | IL1R2 |
| Protein name | Interleukin-1 receptor type 2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P27931 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human IL1R2. AA range:141-190 |
| Specificity | IL-1RII Polyclonal Antibody detects endogenous levels of IL-1RII protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 43kD |
| Background | The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012], |
| Function | function:Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1ra).,similarity:Belongs to the interleukin-1 receptor family.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains., |
| Subcellular location | [Isoform Short]: Secreted .; [Isoform Long]: Cell membrane; Single-pass type I membrane protein. |
| Expression | B-cell,Colon,Ovary, |
Additional Images
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Western Blot analysis of PC12 cells using IL-1RII Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Immunohistochemical analysis of paraffin-embedded human-Ovarian-cancer, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded human-Ovarian-cancer, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded human-colon, antibody was diluted at 1:100
: AO-06-ES4200-100
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