ZNF384 rabbit pAb

ZNF384 rabbit pAb

AO-06-ES4261-100

ZNF384 rabbit pAb 100μL

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Antibody Product Overview

ELK.NoES4261
Product nameZNF384 rabbit pAb
ReactivityHuman;Rat
ApplicationsWB;ELISA
Other nameZNF384; CAGH1; CIZ; NMP4; TNRC1; Zinc finger protein 384; CAG repeat protein 1; CAS-interacting zinc finger protein; Nuclear matrix transcription factor 4; Nuclear matrix protein 4; Trinucleotide repeat-containing gene 1 protein
Size100μL
Unit price ($)248
Human gene ID171017
Human Swiss-ProtQ8TF68
SourceRabbit
IsotypeIgG
TargetZNF384
Fields
Gene nameZNF384
Protein nameZinc finger protein 384
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID
Mouse gene link
Mouse Swiss-Prot
Mouse Swiss link
Rat gene ID171018
Rat gene linkView Rat Gene
Rat Swiss-ProtQ9EQJ4
Rat Swiss linkView Rat Swiss-Prot
ImmunogenThe antiserum was produced against synthesized peptide derived from the N-terminal region of human ZNF384. AA range:1-50
SpecificityZNF384 Polyclonal Antibody detects endogenous levels of ZNF384 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)64kD
Backgroundzinc finger protein 384(ZNF384) Homo sapiens This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011],
Functionalternative products:Additional isoforms seem to exist,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Transcription factor that binds the consensus DNA sequence [GC]AAAAA. Seems to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 8 C2H2-type zinc fingers.,subunit:Interacts with BCAR1.,
Subcellular locationNucleus .
ExpressionBrain,Brain cortex,Testis,

Additional Images

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Western Blot analysis of VEC cells using ZNF384 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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: AO-06-ES4261-100
: 10 Items
Hurry! only 10 items left in stock.

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